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Individuals taking Wegovy should monitor for blood clot-related symptoms

However, the absence of toxicity signals in animal models does not guarantee equivalent safety in humans, and long-term safety data in human populations does not currently exist

However, while it is evident that DPP-4 has the potential to influence glycaemic control, its overall significance for the normal physiological regulation of glucose homeostasis in humans and its role in the pathogenesis of metabolic disease remain to be established

Policy The findings support continuing the use of GLP-1 medications in women with metabolic risk factors who are considering pregnancy, says Cara Dolin, MD, a maternal-fetal medicine specialist, and a coauthor of the research, which was presented at the Society of Maternal-Fetal Medicine pregnancy meeting in February 2026