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Next Steps Semaglutide and tirzepatide are both FDA-approved, well-studied GLP-1 options, while retatrutide remains a promising but investigational medication still working through clinical trials
The Institute for Clinical and Economic Review evaluated injectable semaglutide, oral semaglutide and tirzepatide against lifestyle modification alone
The post presents these as approximate means and stresses that individual results vary
Ask in writing whether anti-obesity medications are an excluded benefit, because an exclusion cannot be appealed on clinical grounds while a medical-necessity denial can
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