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In high blood pressure, it normalizes the blood pressure by relaxing the blood vessels to reduce the pressure on them, thereby improving the blood flow in the body

The transcription and expression of the antioxidant protein glutathione peroxidase 4 (GPX4), as well as mitochondrial function-associated proteins ATP synthase subunit alpha (ATP5A), ubiquinol-cytochrome c reductase core protein 2 (UQCRC2), and cytochrome c oxidase subunit I (MTCO1), were also restored following irisin treatment (Fig

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