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Effects may be less dramatic than the first course if the initial burden was substantially reduced Maintenance: Some community protocols transition to once-yearly courses for ongoing senescent cell management There is no research to validate this approach

Alternatively, embolization or blockage of the internal spermatic vein can be done radiologically, but success rates are less than surgical outcomes, radiation exposure may affect sperm production, and long-term follow-up data is not available

Improves collagen production

Statistical significance was assessed by an unpaired two-tailed t-test in a - i , l - n , and by Ordinary One-Way ANOVA followed by Dunnetts multiple comparisons test in j , k