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NHS approach to B12 deficiency: NICE Clinical Knowledge Summaries recommend investigating B12 deficiency in patients presenting with macrocytic anaemia, unexplained neurological symptoms, or risk factors including pernicious anaemia, gastrectomy, malabsorption disorders, metformin use, proton pump inhibitors, or nitrous oxide exposure

Grip strength and five-repetition maximum in compound lifts offer additional functional metrics that capture the muscular benefits of improved mitochondrial efficiency and glucose uptake in skeletal muscle