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NF-B p65 pathway inhibition occurs through blocking phosphorylation at Ser536 and preventing nuclear translocation, suppressing transcription of pro-inflammatory genes
Excessive accumulation of ECM components is strongly associated with fibrosis [39]
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Mice with a homozygous null mutation for the most abundant glutathione peroxidase, Gpx1, show increased susceptibility to the oxidative stress-inducing agents paraquat and hydrogen peroxide
Clinical investigations using DCE-MRI reveal a stark contrast in BBB performance between healthy individuals and patients diagnosed with PD
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