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The study revealed that the addition of LCZ led to significant alterations in nonvolatile metabolomic profiles, such as increased levels of galactose, amino and nucleotide sugars, fructose and mannose, purine, Phe metabolism, and Arg biosynthesis

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A biweekly injection of a fatty-acylated version of this dual agonist improved body weight, glucose homeostasis and lipid metabolism in DIO mice [91]

Cruz-Jentoft AJ, Baeyens JP, Bauer JM, Boirie Y, Cederholm T, Landi F, Martin FC, Michel JP, Rolland Y, Schneider SM, Topinkova E, Vandewoude M, Zamboni M