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Nei trial clinici randomizzati e controllati (RCT) , come lo studio STEP 1 e successivi, Wegovy ha dimostrato una riduzione media del peso corporeo compresa tra il 15% e il 17% a 68 settimane in soggetti adulti con obesit, senza diabete, in associazione a dieta ipocalorica ed esercizio fisico
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As the pathological immune response in HDFN can arise early in gestation and persist throughout a pregnancy, dosing of FcRn antagonists to treat HDFN would have to be continuously performed throughout gestation
Upper airway disease needs to be taken more seriously with accurate diagnosis of AR, since it is likely that, if effectively treated early, some asthma may be prevented
