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Dipeptidyl peptidase-4 (DPP4), also known as CD26, is a widely expressed serine membrane-anchored ectopeptidase that exists on the surface of different cell types and cleaves dipeptides from the N-terminus, where a proline residue is in a penultimate position [6]
206 Interestingly, chronic GLP-1R activation activates distinct signalling pathways
These changes further reduce cardiovascular risk beyond what weight loss alone would predict
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