Since human clinical trials are essentially nonexistent, the available data comes from anecdotal reports from the biohacking community
Neutrophils can be activated by recognition through Toll-like receptor 2 (TLR2), Toll-like receptor 4 (TLR4), and complement receptors (91), and they are stimulated by pathogenic microorganisms, activated platelets, specific cytokines (such as IL-8 and TNF-), lipopolysaccharides (LPS), and other stimuli (92), finally activating the NADPH oxidase (93)
S2CID 29422959
GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper) is a naturally occurring human copper-binding tripeptide studied extensively across regenerative biology, wound healing, skin science, anti-ageing research, and tissue remodelling for its broad influence on collagen synthesis, antioxidant defence, angiogenesis, and gene expression regulation making it one of the most versatile and widely researched copper peptides in modern regenerative and dermatological science