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Dynamic redox control of NF-kappaB through glutaredoxin-regulated S-glutathionylation of inhibitory kappaB kinase beta
Radu MR, Prdatu A, Duic F, Micu R, Creoiu SM, Suciu N, Creoiu D, Varlas VN, Rdoi VE
In addition, SREBP-1c activation also inhibits carnitine palmitoyltransferase 1 (CPT1) through the generation of Malonyl-CoA, thereby inhibiting fatty acid entry into mitochondria for -oxidation, which further leads to lipid accumulation in the cell (Figure 3)
In humans, two stereospecific families of methionine sulfoxide reductases (MsrA and MsrB) are encoded by a single MSRA gene and three MSRB genes ( MSRB1-3 )
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