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Among epigenetic mechanisms, histone methylation has garnered particular attention for its role in shaping chromatin structure and regulating transcription of key profibrotic genes such as transforming growth factor-beta 1 (TGF-1) and type I collagen (131, 132)
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The stratum corneum admits molecules under 500 Daltons [34]
#6 Skin Flushing (low risk) Temporary skin flushing or redness may occur after injections
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