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Clinical phase 2 studies indicated that resmetirom reduced hepatic fat content (measured by MRI-PDFF), lowered liver enzyme values, improved noninvasive markers of liver fibrogenesis, and decreased liver stiffness
Tirzepatide is a dual GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) receptor agonist
Aetna already wrote the lower threshold into its policy, and Cigna grants exceptions when diabetes stays uncontrolled
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