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Featured Expert Mark Graber, JD Carey School of Law Source: Maryland Matters Next major revolution: The rise of targeted oral psoriasis therapies June 23, 2026 In 2022, deucravacitinib (Sotyktu, Bristol Myers Squibb) became the first TYK2 inhibitor a type of JAK inhibitor approved for moderate to severe plaque psoriasis, changing the clinical landscape, according to Andrew Blauvelt, MD, MBA, adjunct professor of dermatology at the University of Maryland School of Medicine and an investigator for multiple phase 2 and 3 trials for TYK2 inhibitors
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Neuro-humoral actions include modulation of hypothalamic appetite centers, leading to increased satiety and reduced caloric intake, as well as slowing of gastric emptying, which further contributes to appetite suppression and glycemic control [74]
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