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Both candidates utilize the KITE DuoCore construct, an investigational design that incorporates two independent CARs intended to address challenges such as antigen loss

First, unlike other DPP-4 inhibitors that are excreted largely in urine, linagliptin is mainly eliminated by a biliary route [131] and therefore does not require dose adjustment in patients with kidney disease [132, 133]

Samples were drawn from Panels LTD online panel of over 30,000 active Israeli members, supplemented with cellphone and landline contacts and Hebrew-language outreach to Haredi communities

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