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North America currently leads the global GLP-1 analogue market, driven by high obesity rates, strong reimbursement frameworks, and proactive healthcare systems

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The primary reason is that the glucose-lowering action of metformin, when used alone, is at least as effective as that of any other oral glucose-lowering drug, without promoting weight gain and only rarely causing excessively low blood sugar

GLP-1 Affordability Challenges Consumers enrolled in high-deductible health plans (HDHPs) often encounter even greater affordability challenges because prescription drug coverage may not significantly reduce costs until deductibles are met