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XL413, an inhibitor of CDC7 kinase, effectively induced senescence in liver cancer cells, simultaneously sensitizing them to the senolytic action of the mTOR inhibitor, AZD8055 [136]
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Agerelated declines of 13 % per year in GH, melatonin, and cortisol further underscore the need for targeted interventions
Other top GSTO1 inhibitors too showed cytotoxicity in a panel of cancer cell lines (Supplementary Table 9)
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