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GLP-1 medications are effective, but they certainly arent the onlyor inherently the bestoption for people who need to address obesity and manage their weight

The Phase 2b VESPER-3 study tested how people on PF3944 would fare after moving to a less frequent dose

The results showed that compared to placebo, GLP-1 receptor agonists reduced the risk of kidney failure by 16% and the worsening of kidney function by 22% (defined by a drop in estimated glomerular filtration rate a measure of how much blood the kidneys filter clean every minute of at least 50%)

The common side effects of retatrutide are largely similar to Zepbound , since they affect GLP-1 and GIP