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Most interestingly, hybrids 14 , 22 and 23 showed an improved efficacy compare to the native peptide 1 (Fig
This protection extends to potential benefits for inflammatory bowel conditions, such as Crohns disease and ulcerative colitis, although further clinical studies are needed
The groups most likely to develop B12-related hair and skin changes are the same ones at risk for deficiency generally: vegans and vegetarians, adults over 50, people on long-term metformin or proton pump inhibitors, anyone who's had bariatric surgery, and people on GLP-1 protocols whose reduced appetite has significantly lowered their overall nutrient intake for an extended period
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