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Pioglitazone has demonstrated efficacy but carries risks of weight gain, fluid retention, heart failure, and bone fractures

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Yet, the success of this transformation will depend on addressing structural barriers such as reimbursement gaps, manufacturing constraints, and equitable global access

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Most importantly, exosomes have been shown to transport iron out of the cell to regulate ferroptosis ( Publishers Note All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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The efficacy of IDegLira (insulin degludec/liraglutide combination) in adults with type 2 diabetes inadequately controlled with a GLP-1 receptor agonist and oral therapy: DUAL III randomized clinical trial

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