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Chemical Makeup Molecular Formula: C 228 H 388 N 86 O 64 Molecular Weight: 5358.05 g/mol Other Known Titles: Forkhead box protein O4, Proxofim, FOXO4a, AFX, AFX1, MLLT7 Research and Clinical Studies FOXO4-DRI Peptide and Senescence FOXO4-DRI peptide research indicates that the peptide may not wholly stop cell senescence

Variability Across Study Designs Safety signals in published studies vary due to differences in: species used (rodents vs other models) dosing magnitude route of administration model type (injury-induced vs healthy tissue) study duration This variability limits the ability to draw broad conclusions

In rat tendon studies, administration accelerated outgrowth, fibroblast migration, and post-injury cellular survival (PMID 21030672)

More severe side effects are rare but can include low potassium, headache, dizziness, and chest pain