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[1] [3] Decisions about whether to continue or temporarily pause these medications are individualised based on factors such as: The specific GLP-1 medication and dosage Whether you're in a dose-escalation phase Presence of gastrointestinal symptoms Type and urgency of surgery Individual risk factors for aspiration Standard UK fasting guidance typically recommends 6 hours for solids and 2 hours for clear fluids before surgery

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This is in contrast to its rival diabetes injectable drug semaglutide (Ozempic), a GLP-1 receptor agonist that targets one hormone

Who Should Not Follow It Without Supervision Several groups face elevated risks on very-low-calorie diets