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Early data and smaller studies on GLP-1s suggest that these drugs can improve insulin sensitivity and stabilize blood glucose even before significant weight loss occurs, which may be beneficial to some people
Notably, the STEP TEENS trial showed that semaglutide 2.4 mg, administered once weekly via subcutaneous injection, can be used in individuals aged 12 years and older, as adolescents with obesity treated with semaglutide experienced a significant reduction in BMI compared with placebo, along with improvements in several cardiometabolic risk factors [47]
Laboratory and animal studies show encouraging signs of slower biological aging
A 5mg vial lasts 17-50 days
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