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A new approach for the prevention and treatment of cardiovascular disorders
Bolontrade MF, Worth LL, Zhou Z, Andreeff M , Kleinerman ES
GLP-1RAs stimulate NO production and eNOS activation, eliciting vasorelaxation in arterial endothelium in vitro [104]
Compared to individuals without diabetes, patients with diabetes present a higher atheroma volume, a smaller arterial lumen, more rapid progression of atherosclerosis, more macrophage accumulation, and a higher incidence of thrombus [15, 16]
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