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The article lists body composition, specifically lean versus fat mass, as a maintenance biomarker and says preserving muscle during weight loss predicts better metabolic stability and lower rebound risk after treatment
In the SURMOUNT-1 trial, Mounjaro helped people lose up to 22.5% of their starting body weight at 72 weeks
Furthermore, the activation of the GIP receptor also improved glucose metabolism in diet-induced obese mice without changing body weight or fat mass [69]
A 2017 study showed real benefits for people with fatty liver disease who got glutathione treatment
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