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When stratified by administration route, the mean percentage changes were: Intramuscular (IM): 307% Oral: 285% Sublingual: 199% IM administration showed the highest average B12 increase, although oral and sublingual routes also yielded substantial improvements, supporting their use as effective and less invasive alternatives

Better Absorption Compared to Oral Supplements For individuals with absorption issues due to conditions like pernicious anemia or gastrointestinal disorders, injections are a more reliable way to ensure adequate B12 levels

Consider the neuropathys severity and the patients health

Both are GI-forward