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In vitro studies using normal human epidermal keratinocytes revealed that treatment with glutathione amino acid precursors significantly increased both GSH and glutathione disulfide levels, leading to an improved GSH/glutathione disulfide ratio, which is a key indicator of cellular redox balance
The most common dosages 31 used in studies 32 range from 2000-4000 mg of myo-inositol and 50-100 mg of d-chiro-inositol a day to match the physiological ratio that exists in the body (40 to 1 of MI to DCI 33 )
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