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3,4 GLP-1RAs mimic the action of endogenous GLP-1, activating GLP-1R, thereby enhancing insulin secretion, inhibiting glucagon release, delaying gastric emptying, and reducing food intake through central appetite suppression
In addition, tryptophan-derived indoles further attenuated neuroinflammation via inhibiting pro-inflammatory cytokine production in microglia and astrocytes (Rothhammer et al., 2018, 2016)
doi: 10.1146/annurev-med-060513-093205 11 MaynardCLElsonCOHattonRDWeaverCT
nevertheless, it may engage many molecular pathways that regulate healing processes
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