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The effects of FGF23 are exerted primarily within the kidney where its actions result in increased phosphate excretion (decreased phosphate reabsorption) and suppression of calcitriol synthesis via inhibition of the expression of the CYP27B1 gene that encodes the PTH-inducible 1--hydroxylase enzyme
May support mental focus
PT-141 was developed by Palatin Technologies and is currently in clinical trials
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