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This modification dramatically reduces binding to IGF-binding proteins (IGFBPs), extending its half-life from ~15 minutes (native IGF-1) to 2030 hours
Addeo, A., Friedlaender, A., Banna, G
Mice that dont easily gain weight have less NNMT
Research-grade specs Class: Small-molecule NNMT inhibitor (not a peptide) Molecular weight: 177 g/mol Vial size: 50 mg Format: Lyophilized powder Mechanism studied: NNMT inhibition and intracellular NAD availability This compound is manufactured under cGMP conditions in Dallas, Texas, and independently verified to 99% purity through HPLC and mass spectrometry analysis, with a batch-specific Certificate of Analysis provided for every order
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