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J Headache Pain (2016) 17:49.10.1186/s10194-016-0631-z 57 YinZFangYRenLWangXZhangALinJet alAtorvastatin attenuates NF-kappaB activation in trigeminal nucleus caudalis in a rat model of migraine

GLP-1 receptor agonists such as Saxenda and Wegovy work, with clinical trial evidence behind them roughly 6% and 16% body weight reduction respectively over 68-week trials