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Studies indicate that in the presence of insulin, GIP enhances phosphorylation of protein kinase B (PKB/Akt) and inhibits phosphorylation of LKB1 and AMPK, leading to activation of lipoprotein lipase (LPL) and lipid accumulation
(2024) Evaluating the impact of testosterone replacement therapy on carotid atherosclerosis: a systematic review and meta-analysis Haider SH, Irfan A, Sheikh SM, et al
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In 8 options it covers three FDA black-box warning conditions (MTC family history, MEN2 family history, pancreatitis), two absolute GLP-1 contraindications (Type 1 diabetes, pregnancy), and two safety-critical behavioral flags (active eating disorder, substance abuse)
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