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Retatrutide is a potent triple agonist peptide specifically designed to target the GLP-1, GIP, and glucagon (GCGR) receptors
In a study with radiolabelled liraglutide, no intact liraglutide was excreted in urine or faeces, and low levels of metabolites were detected in plasma, indicating that the drug is completely degraded into peptides, amino acids and fatty acid fragments within the body [32]
PT-141 bypasses the endocrine system entirely
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