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However, innate immune activation also appeared as a dominant signature, specifically interferon- (false discovery rate (FDR) 20,000 g at 4 C for 15 min

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In humans, the biotin-requiring enzymes include acetyl-CoA carboxylase (ACC: humans express two distinct ACC genes), pyruvate carboxylase (PC), propionyl-CoA carboxylase (PCC), and 3-methylcrotonyl-CoA carboxylase (3MCC)