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However, tolerability, discontinuation rates, and comparative efficacy will be key watchpoints
Semaglutide# Semaglutide was specifically developed and approved for weight management at higher doses: STEP 1 (1,961 adults without T2D): 14.9% mean weight loss at 2.4 mg over 68 weeks
The GIP receptor activation in tirzepatide appears to moderate the gastrointestinal effects of GLP-1 receptor activation
GLP-1 receptor agonists and risk for cirrhosis and related complications in patients with metabolic dysfunction-associated steatotic liver disease
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