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Jessica Atieh, MD
The results were striking: participants lost an average of 14.9% of their body weight over 68 weeks
Dimethyl fumarate (DMF), an FDA-approved drug prescribed for the treatment of multiple sclerosis (55, 56), activates NRF2 by disrupting its interaction with KEAP1 ( Figure 7A ), allowing NRF2 to translocate to the nucleus and become transcriptionally active (5557)
collagen type IV and fibronectin coating)
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