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Frequency count categorized three-day average nutrient intake of GLP-1RA participants compared to dietary reference intake
For the once-weekly subcutaneous formulation, the SUSTAIN program (Semaglutide Unabated Sustainability in Treatment of Type 2 Diabetes) included 13 separate randomized clinical phase 3a and 3b trials ( Table 1 Overview of Phase 3 studies of oral semaglutide (PIONEER) and subcutaneous semaglutide (SUSTAIN) ( *Phase 3b trials all others are phase 3a trials CKD, chronic kidney disease
This structured approach reduces the likelihood of experiencing severe gastrointestinal side effects such as nausea, vomiting, and diarrhoea
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