The LOX has been demonstrated as crucial contributors for normal embryonic development of various tissue and organ systems, including cardiovascular (Martinez-Gonzalez et al., 2019), and respiratory systems (Maki et al., 2002
(2019) Targeting glutathione metabolism: partner in crime in anticancer therapy, Nutrients , 11 , 1926, doi: Kengen, J., Deglasse, J
Around S = 1.4, the GS flux starts to increase more slowly while the GPX flux still increases at roughly the same rate as S increases, so the GSH curve starts to level off and reaches a maximum at S = 1.8
Stability of GSH under large input fluctuations Hepatocytes are seldom at steady state [21] because they receive large protein inputs during and shortly after meals and relatively little protein input between meals