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The 72-week STEP UP trial was a randomised, double-blinded, parallel-group, placebo-controlled, superiority trial designed to evaluate the efficacy of semaglutide 7.2 mg with semaglutide 2.4 mg and placebo as an adjunct to lifestyle intervention
Vniant and Shu-Chen Lu of Amgen Research
This review walks you through how it works, what it costs, and whether Ros weight-loss program lives up to the hype
In another trial using 15 mg of tirzepatide (the maximum dose of Mounjaro and Zepbound), patients lost just over 20% of their body weight after 72 weeks
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