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Whether youre on Wegovy, Ozempic, Mounjaro, or a compounded semaglutide, that uncomfortable back-up is one of the most frustrating GLP-1 side effects
Yes, obesity trials have shown that participants using incretin mimetic agents like semaglutide (Ozempic, Wegovy) or tirzepatide (Mounjaro, Zepbound) lost 10% or more of their muscle mass in 68- to 72-week long clinical studies, which equates to roughly 20 years of muscle loss due aging, according to experts
The inhibition was specific for mitophagy because neither macro- nor micro-ATG was altered
Galione A, White A, Willmott N, Turner M, Potter BV, Watson SP
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