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Oral administration of LGG has been shown to increase butyric acid concentrations in the intestinal mucosa and serum, activate Treg cell activation in bone marrow (BM) CD8+T cells to up-regulate the expression of the Wnt ligand, Wnt10b, and increase bone formation, thereby preventing osteoporosis-induced fractures
The monthly subcutaneous form is simultaneously the longest-interval dosing in the field
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