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Using sterile water for repeated draws over an extended period increases the risk of bacterial growth in the vial, as the solution contains nothing to inhibit it
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Notably, GLP-1 have shown the ability to reduce the pleasurable effects of nicotine, as evidenced by decreased nicotine-induced movement, reduced release of dopamine (a neurotransmitter associated with reward) in the nucleus accumbens, and a decrease in conditioned preference for places associated with nicotine use
15 Dahl, D., et al., Effect of Subcutaneous Tirzepatide vs Placebo Added to Titrated Insulin Glargine on Glycemic Control in Patients With Type 2 Diabetes: The SURPASS-5 Randomized Clinical Trial
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