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SAR425899, which has yielded early promising results regarding weight and hyperglycemia, 51,52 has undergone a phase 2 study, where it was administered in combination with metformin vs, placebo plus metformin and liraglutide plus metformin, in diabetic obese patients (NCT02973321)
In a recent webinar, Dr
Examples: liraglutide, semaglutide, dulaglutide, occasionally dual agents (GLP-1 + GIP like tirzepatide)
The thyroid contains GLP-1 receptors, the long-term activation of which could plausibly be carcinogenic
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