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Multiple molecular targets have been studied in the fundamental processes of curcumin incurring cell death in CRC ( via the extrinsic pathway
Tanaka Y, Abe Y, Oto Y, et al
In contrast to the limited therapeutic gains observed with fCaCO3-PEG + X-ray irradiation (glucose metabolic regulation alone) or PFC@fSiO2-PEG + X-ray exposure (hypoxia attenuation alone) compared to conventional radiotherapy, PFCE@fCaCO3-PEG markedly enhanced radiotherapy efficacy, resulting in a cure for 4 of 5 mice
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