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148 QuinlanC

Variants from the site-saturation library covered broader range of selectivities than those from the random mutagenesis library were biased towards selectivity for DHIQ and S -THIQ, which follows the selectivity of the template (Fig

Tirzepatide also changes its structure to get longer-lasting effects, but its chemical structure is different to make GIP receptor binding and GLP-1 activation work better