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Weight-loss medications are often handled like a locked door with several keys

In the matched cohort of GLP-1RA and SGLT2i, the risk of cardiovascular mortality in GLP-1RA was not significantly different from that in SGLT2i (HR, 0.84

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5,6 GLP-1RA medications primarily work by mimicking endogenous incretins that help regulate key metabolic pathways such as -oxidation of fatty acids and glycogenolysis by influencing insulin and glucagon secretion