Epigenetic changes can alter gene expression patterns without altering the DNA sequence itself 105
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These findings together suggest that NAC, particularly alone or combined with IFN-, enhances ER stress response in endometriotic cells
55 In esophageal squamous cell carcinoma (ESCC), QSOX2 promotes disulfide bond formation in TSC2, enhancing its phosphorylation by Akt and activating the mTOR/4E-BP1/c-Myc axis, thereby upregulating CSC markers (e.g., CD44, Notch1) and promoting platinum resistance