36 studies reviewed (1993-2024) Mechanism: NO system modulation, VEGF/angiogenesis, FAK-paxillin migration pathway Clinical Status: Not FDA or EMA approved
Male: Potential benefit for varicocele-related damage and testicular inflammation
Non-prescription and compounded peptides such as BPC-157, CJC-1295/Ipamorelin, AOD-9604, and MOTS-c are not FDA-approved for weight loss and lack the same regulatory oversight and clinical safety data as the GLP-1 drugs in the table above, which is why they should only be used under the guidance of a licensed medical provider who can order lab work, personalize dosing, and monitor for side effects throughout treatment
licensed UK options include orlistat, semaglutide (Wegovy, TA875), and liraglutide (Saxenda, TA664), all with established safety profiles