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These side effect are is often reduced by taking prolonged released formulation or taking metformin with food
Another study reported that GF C57BL/6 J mice exhibited hypolocomotion at the age of 4 weeks but no change in locomotion at the age of 12 weeks 16
These symptoms may indicate complications requiring immediate medical evaluation and potential treatment modification or discontinuation
Sensitivity Analyses Our findings remained generally consistent when the study design was modified from an intention-to-treat to a per-protocol approach
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