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Residues in the anterior and posterior regions of TAD2 and the C-terminus of p53 TAD appear to be important for the interaction with FOXO4 FHD
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85,86 HSYA also inhibits the transcription and translation of sarcoma-associated genes, suppresses phosphorylation of downstream signaling pathways, and reduces expression of proteins related to platelet activation by upregulating miR-9a-5p
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